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ACLS Medications
Epinephrine
Mechanism of Action
Stimulates adrenergic receptors and is not dose dependent like dopamine.
Epinephrine
Indications
Cardiac arrest
VF; VT; asystole; PEA
Symptomatic bradycardia
After atropine; alternative to dopamine
Severe hypotension
When atropine and pacing fail; hypotension accompanying bradycardia; phosphodiesterase enzyme inhibitors
Anaphylaxis; severe allergic reactions
Combine with large fluid volume; corticosteroids; antihistamines
Pulseless electrical activity or PEA refers to a cardiac arrest situation in which a heart rhythm is observed on the electrocardiogram that should be producing a pulse , but is not.
Under normal circumstances, electrical activation of muscle cells precedes mechanical contraction of the heart (known as electromechanical coupling ).
In PEA, there is electrical activity, but the heart either does not contract or there are other reasons why this results in an insufficient cardiac output to generate a pulse and supply blood to the organs
Pulseless electrical activity
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